Colostrum has essential roles in the first hours of the piglets life. It is important for piglets due to its nutrient composition. Composition of colostrum is variable. There are differences between breeds and sows which are caused due to lactation stage, nutrition before parturition, genetics, individuality and many other factors. Colostrum is source of important nutrients like energy, immunoglobulins, fats and minerals. Minerals are important and essential for their structural functions in the body of piglets, in the regulatory functions of body fluids and in the erythropoiesis. The aim of this study was to determine changes in the concentration of minerals in the colostrum of sows during the first 48 hours after parturition. The concentration of minerals of sow colostrum was determined in 5 sows (White Improved Breed in the second litter). Minerals were analyzed with ContrAA®700 (Analytikjena, Germany). From birth of the first piglet to 48. hour, in this time period were concentrations of minerals in colostrum in these intervals: Ca from 0.44 g.kg-1 to 0.86 g.kg-1, P: 1.30 – 1.41 g.kg-1, Na: 0.73 – 1.46 g.kg-1, K: 1.03 – 1.44 g.kg-1, Cu: 2.93 – 4.26 mg.kg-1, Fe: 1.39 – 2.06 mg.kg-1, Zn: 12.84 – 21.68 mg.kg-1 and Mg 73.00 – 94.50 mg.kg-1.